TO TOP


Prof. Dr. Carsten Saft

Neurodegeneration, Huntington-Center NRW
Clinic of Neurology
Faculty of Medicine
Universitätsklinikum St. Josef- und St. Elisabeth- Hospital
Gudrunstr. 56
44791 Bochum

Phone: +49 (0)234 509-6405
Email: carsten.saft@ruhr-uni-bochum.de


Homepage
orcid.org/0000-0002-3983-7292
Prof. Dr. med. Carsten Saft
Prof. Dr. med. Carsten Saft
Research Interests

Huntington’s disease (Treatment, Biomarker), Movement disorders

Saft, C. (2022). Huntington’s disease: disappointments and new beginnings. Lancet Neurology, 21(7), 582–584. https://doi.org/10.1016/s1474-4422(22)00189-2

Pinto, R. J., Arning, L., Giordano, J., Razghandi, P., Andrew, M. A., Gillis, T., Correia, K., Mysore, J. S., Urtubey, D. M. G., Parwez, C. R., Von Hein, S. M., Clark, H. L., Nguyen, H. P., Förster, E., Beller, A., Jayadaev, S., Keene, C. D., Bird, T. D., Lucente, D., Saft, C., . . . Wheeler, V. C. (2020). Patterns of CAG repeat instability in the central nervous system and periphery in Huntington’s disease and in spinocerebellar ataxia type 1. Human Molecular Genetics, 29(15), 2551–2567. https://doi.org/10.1093/hmg/ddaa139

Tabrizi, S. J., Leavitt, B. R., Landwehrmeyer, G. B., Wild, E. J., Saft, C., Barker, R. A., Blair, N. F., Craufurd, D., Priller, J., Rickards, H., Rosser, A., Kordasiewicz, H. B., Czech, C., Swayze, E. E., Norris, D. A., Baumann, T., Gerlach, I., Schobel, S. A., Paz, E., . . . Lane, R. M. (2019). Targeting Huntingtin Expression in Patients with Huntington's Disease. The New England Journal of Medicine, 380(24), 2307–2316. https://doi.org/10.1056/nejmoa1900907

Van Well, E. M., Bader, V., Patra, M., Sánchez-Vicente, A., Meschede, J., Furthmann, N., Schnack, C., Blusch, A., Longworth, J., Petrasch-Parwez, E., Haass, C., Arzberger, T., Trümbach, D., Angersbach, L., Showkat, C., Sehr, D. A., Berlemann, L. A., Goldmann, P. L., Clement, A. M., Saft, C., . . . Winklhofer, K. F. (2019). A protein quality control pathway regulated by linear ubiquitination. The EMBO Journal, 38(9). https://doi.org/10.15252/embj.2018100730

Saft, C. (2017). Identifying modifiers of Huntington’s disease progression. Lancet Neurology. https://doi.org/10.1016/s1474-4422(17)30179-5