The Research Department of Neuroscience was founded in 2010 as part of the future concept "Research Campus RUB" of Ruhr University Bochum that aims to support excellent research. The RDN was financially supported by the Ministry for Innovation, Science, Research, and Technology of the state North Rhine-Westphalia until the end of 2010. Since the end of 2025, the Science Hub Neuroscience (SHN) has taken over the role of the former RDN as its follow-up structure.

The organs of the Science Hub Neuroscience are:

• the General Assembly, which is made up of all PIs of the SHN. Scientists can apply to become members of the SHN if they meet the membership criteria set out in the SHN's by-laws.
• the Executive Board, which consists of 12 members, including the Speaker's Committee.
• the Speaker's Committee, consisting of the speaker Prof. Dr. Jonas Rose and two vice speakers Prof. Dr. Sigrid Elsenbruch and Prof. Dr. Konstanze Winklhofer.

The Executive Board as well as the Speaker's Committee are elected every three years by the General Assembly. The Executive Board is the decision-making body of the Science Hub Neuroscience, whereby petitions, proposals and decisions submitted to the General Assembly are taken into account. The speaker manages the business and represents the SHN externally. The speaker is supported by the vice speakers and the Science Manager of the Science Hub.

The legal basis for executive right comprises the by-laws of the Science Hub Neuroscience, which were adopted by the General Assembly and approved by the Rectorate of the Ruhr University Bochum.