Optical Imaging Lab
Institute for Neuroinformatik
Faculty for Computer Science
Ruhr University Bochum
Universitätsstr. 150
44801 Bochum
Room:
NB 3/32
Phone:
+49 (0)234 32-27845
Email:
dirk.jancke@ruhr-uni-bochum.de
We investigate the brain's capacities for plastic reorganization and learning. We use optical imaging techniques combined with modelling to decipher computational strategies of neural networks leading to perception and behavior. In combination with optogenetics (i.e., light stimulation and recordings of specific target neurons and neuronal subnetworks) our approach provides access to theoretical and experimental questions dealing with the highly dynamic activity patterns across the brain.
Jancke, D., Herlitze, S., Kringelbach, M. L., & Deco, G. (2022). Bridging the gap between single receptor type activity and whole-brain dynamics. The FEBS Journal, 289(8), 2067–2084. https://doi.org/10.1111/febs.15855
Eickelbeck, D., Karapinar, R., Jack, A., Suess, S. T., Barzan, R., Azimi, Z., Surdin, T., Grömmke, M., Mark, M. D., Gerwert, K., Jancke, D., Wahle, P., Spoida, K., & Herlitze, S. (2019). Camello-XR enables visualization and optogenetic control of Gq/11 signals and receptor trafficking in GPCR-specific domains. Communications Biology, 2, 60. https://doi.org/10.1038/s42003-019-0292-y
Kozyrev, V., Staadt, R., Eysel, U. T. & Jancke, D. (2018). TMS-induced neuronal plasticity enables targeted remodeling of visual cortical maps. Proceedings of the National Academy of Sciences of the United States of America, 115(25), 6476–6481. https://doi.org/10.1073/pnas.1802798115
Rekauzke, S., Nortmann, N., Staadt, R., Hock, H. S., Schöner, G. & Jancke, D. (2016). Temporal Asymmetry in Dark–Bright Processing Initiates Propagating Activity across Primary Visual Cortex. The Journal of Neuroscience, 36(6), 1902–1913. https://doi.org/10.1523/jneurosci.3235-15.2016
Nortmann, N., Rekauzke, S., Onat, S., König, P. & Jancke, D. (2015). Primary Visual Cortex Represents the Difference Between Past and Present. Cerebral Cortex, 25(6), 1427–1440. https://doi.org/10.1093/cercor/bht318
Kozyrev, V., Eysel, U. T. & Jancke, D. (2014). Voltage-sensitive dye imaging of transcranial magnetic stimulation-induced intracortical dynamics. Proceedings of the National Academy of Sciences of the United States of America, 111(37), 13553–13558. https://doi.org/10.1073/pnas.1405508111
Palagina, G., Eysel, U. T. & Jancke, D. (2009). Strengthening of lateral activation in adult rat visual cortex after retinal lesions captured with voltage-sensitive dye imaging in vivo. Proceedings of the National Academy of Sciences of the United States of America, 106(21), 8743–8747. https://doi.org/10.1073/pnas.0900068106
Jancke, D., Chavane, F., Naaman, S. & Grinvald, A. (2004). Imaging cortical correlates of illusion in early visual cortex. Nature, 428(6981), 423–426. https://doi.org/10.1038/nature02396
Jancke, D. (2000). Orientation Formed by a Spot’s Trajectory: A Two-Dimensional Population Approach in Primary Visual Cortex. The Journal of Neuroscience, 20(14), RC86. https://doi.org/10.1523/jneurosci.20-14-j0005.2000
Jancke, D., Erlhagen, W., Dinse, H. R., Akhavan, A. A., Giese, M. A., Steinhage, A. & Schöner, G. (1999). Parametric Population Representation of Retinal Location: Neuronal Interaction Dynamics in Cat Primary Visual Cortex. The Journal of Neuroscience, 19(20), 9016–9028. https://doi.org/10.1523/jneurosci.19-20-09016.1999